Sintim, Herman, O.

Drug Discovery Professor of Chemistry
Organic Chemistry/Chemical Biology, Purdue University
DRUG 123/BRWN 4103A, Purdue Univ, West Lafayette, IN 47907

Research Interests:

  • New anticancer agents targeting G-quadruplexes, PARP enzymes and kinases.
  • The chemical biology of bacterial communication, virulence factors production and biofilm formation (quorum sensing and c-di-GMP/c-di-AMP signaling in bacteria).
  • The discovery of new antibiotics with novel modes of action.
  • The catalytic cycle of total syntheses of complex bioactive molecules and the discovery of new reaction methodologies.
  • New DNA nanostructures and machines for bioanalyte detection.