Li, Yuxing

Dr. Yuxing Li’s lab studies how B cells, a critical part of the immune system, respond to viral infection, and applies these findings toward antibody discovery and the development of vaccines and therapeutics to treat viral infections.

Dr. Li’s work has focused on defining broadly neutralizing antibody responses elicited by HIV-1 envelope glycoproteins during natural infections and in animal models. These findings contributed substantially to the in-depth understanding of HIV broadly neutralizing antibody response and the subsequent discovery of broadly neutralizing monoclonal antibodies targeting the HIV envelope glycoprotein receptor binding site, and have important implications for vaccine and immunotherapeutics development